Human Serum Albumin
|Catalog Number :||A002|
|Available Size :||1g, 5g, 10g|
|Synonyms :||Serum albumin, ALB, PRO0883, PRO0903, PRO1341, DKFZp779N1935, GIG20, GIG42, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696, SA, HSA.|
|Description :||Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Mutations in this gene on chromosome 4 result in various anomalous proteins. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. The human albumin gene is 16,961 nucleotides long from the putative 'cap' site to the first poly (A) addition site. It is split into 15 exons which are symmetrically placed within the 3 domains that are thought to have arisen by triplication of a single primordial domain.
HSA is widely used to stabilize blood volume generally from donors but the fear of contamination such as HIV & Hepatitis has enticed great interest in the recombinant form which is identical to the natural blood.
|Source :||INNOzymeⓇ recombinant human serum albumin is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)|
|Purity :||Greater than 98% by SDS-PAGE gel and HPLC analyses.|
|Endotoxin Level :||<0.05 EU/µg|
|Cross Reactivity :||Mouse, Rabbit, Rat, Human|
|Research Interests :||Formulation of Protein Therapeutics, Cell storage:Cryopreservation, Vaccine formulation and manufacturing, Development of mammalian cell cultures, Infertility treatments, Coating for medical devices, Drug delivery, in vivo diagnostics|
|Research Use Only. Not for use in diagnostic or therapeutic procedures.