Human lactoferrin

Human lactoferrin

Catalog Number : L001
Available Size : 100mg, 500mg, 1g
Synonyms : Lactotransferrin, Lactoferrin, Growth-inhibiting protein 12, Talalactoferrin, LTF, GIG12, LF, HLF2, Neutrophil Lactoferrin.
Description : Lactoferrin is a glycoprotein that belongs to the transferrin family of iron binding proteins. It is found in human breast milk as well as most epithelial surface secretions including tears, nasogastric, saliva, and bronchial. Lactoferrin binds 2 molecules of iron with very high affinity. Lactoferrin inhibits bacterial growth by withholding iron, its N-terminal region is an antimicrobial peptide. Lactotransferrin acts synergistically with lysozyme to potentiate the activity of both proteins. The multifunctional protein lactoferrin has many physiological possible roles. It is often referred to as an innate defense protein and frequently serves as the first line of defense in protection against pathogens. It has been shown to have the ability to bind iron, it is a natural anti-bacterial, anti-fungal and anti-viral, it is an antioxidant and it also has immunomodulatory properties. It has many beneficial properties, which make it a good candidate for a number of product applications. Considerable research is currently going on to explain the various suggested biological functions of lactoferrin.
Source : INNOzyme recombinant human LTF is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level : <0.05 EU/µg
Biological Activity : The ED50 was determined by the dose-dependent stimulation with FGFb 10ng/ml of the proliferation of human primary fibroblasts was found to be in the range of 50 ug/ml.
Cross Reactivity : Mouse, Rabbit, Rat, Human, Bovine
Research Interests : Immune System, Cancer, Allergy, Aging
Research Use Only. Not for use in diagnostic or therapeutic procedures.
Animal-free
Mouse-free
Virus-free
Bacteria-free
Endotoxin-free