Enterokinase (light chain)

Recombinant Human Enterokinase (light chain)

Catalog Number : E001
Available Size : 20IU, 50IU, 100IU, 500IU
Synonyms : Enteropeptidase, EC, Enterokinase, Serine protease 7, ENTK,TMPRSS15, MGC133046, Transmembrane Protease Serine 15.
Description : Enteropeptidase or enterokinase is an enzymeinvolved in human digestion. It is produced by cells in the duodenum wall, and is secreted from duodenum's glands, the crypts of Lieberk?hn, whenever ingested food enters the duodenum from the stomach. Enteropeptidase has the critical job of turning trypsinogen(a zymogen) to trypsin, indirectly activating a number of pancreaticdigestive enzymes. Enteropeptidase is a serine proteaseenzyme(EC3.4.21.9). Enteropeptidase is a part of the Chymotrypsin-clan of serine proteases, and is structurally similar to these proteins. Recombinant Human Enterokinase is a specific protease that cleaves after the sequence Asp-Asp-Aps-Aps-Lys. The light chain of enteropeptidase has full enzymatic activity. No other protease activity was detected. Human enteropeptidase binds specifically to STI-agarose. The affinity purifed Human Enterokinase contains amino acids from 785 to 1019 (235 amino acids, MW ~43 kDa).
Source : INNOzyme recombinant human Enterokinase is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level : <0.05 EU/µg
Biological Activity : Sequentially cleaves carboxyl side of D-D-D-D-K.
Research Interests : Production of recombinant proteins.
Research Use Only. Not for use in diagnostic or therapeutic procedures.