Recombinant Human VEGF-165

Catalog Number : E003
Available Size : 10µg, 100µg, 500µg, 1mg
Synonyms : Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen
Description : VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF165 is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Source : INNOkine recombinant human Enterokinase is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level : <0.05 EU/µg
Biological Activity : Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.
Cross Reactivity : Cow, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout, Human, Chicken, Leech, Zebra Fish Embryo, Gelatin Microparticles, Rat + Chicken, Human + Mouse
Research Interests : Angiogenesis/Cardiovascular, Cancer, Inflammation, Proliferation
Research Use Only. Not for use in diagnostic or therapeutic procedures.