| Catalog Number : |
K001 |
| Available Size : |
10µg, 100µg, 500µg, 1mg |
| Synonyms : |
Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 |
| Description : |
Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues. |
| Source : |
INNOkineⓇ recombinant human KGF is produced in rice suspension cells (Oryza sativa L. cv. Dongjin) |
| Purity : |
Greater than 98% by SDS-PAGE gel and HPLC analyses. |
| Endotoxin Level : |
<0.05 EU/µg |
| Biological Activity : |
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. |
| Cross Reactivity : |
Mouse, Rat, Human, Leech, N/A |
| Research Interests : |
Angiogenesis/Cardiovascular, FGF Superfamily, Proliferation, Stem cells & Differentiation, Wound Healing |
| Research Use Only. Not for use in diagnostic or therapeutic procedures. |
