Recombinant Human KGF (FGF-7)

Catalog Number : K001
Available Size : 10µg, 100µg, 500µg, 1mg
Synonyms : Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7
Description : Keratinocyte Growth Factor (KGF/FGF-7) is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of variety of tissues, by promoting cellular proliferation and differentiation. KGF/FG-7 is a mitogen factor specific for epithelial cells and keratinocytes and signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.
Source : INNOkine recombinant human KGF is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level : <0.05 EU/µg
Biological Activity : The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Cross Reactivity : Mouse, Rat, Human, Leech, N/A
Research Interests : Angiogenesis/Cardiovascular, FGF Superfamily, Proliferation, Stem cells & Differentiation, Wound Healing
Research Use Only. Not for use in diagnostic or therapeutic procedures.