Recombinant Human FGF-acidic

Catalog Number : F001
Available Size : 10µg, 100µg, 500µg, 1mg
Synonyms : Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
Description : FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues.
Source : INNOkine recombinant human FGF-acidic is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin Level : <0.05EU/µg
Biological Activity : Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.

Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.

Cross Reactivity : Cow, Mouse, Pig, Rat, Shark, Squid, Human, Hamster, Hagfish, Leech, N/A
Research Interests : Angiogenesis/Cardiovascular, Cancer, Cell Culture, FGF Superfamily, Neurobiology, Proliferation, Stem cells & Differentiation, Wound Healing
Research Use Only. Not for use in diagnostic or therapeutic procedures.