Recombinant Human FGF-acidic
|Catalog Number :||F001|
|Available Size :||10µg, 100µg, 500µg, 1mg|
|Synonyms :||Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta|
|Description :||FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues.|
|Source :||INNOkineⓇ recombinant human FGF-acidic is produced in rice suspension cells (Oryza sativa L. cv. Dongjin)|
|Purity :||Greater than 98% by SDS-PAGE gel and HPLC analyses.|
|Endotoxin Level :||<0.05EU/µg|
|Biological Activity :||Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.
|Cross Reactivity :||Cow, Mouse, Pig, Rat, Shark, Squid, Human, Hamster, Hagfish, Leech, N/A|
|Research Interests :||Angiogenesis/Cardiovascular, Cancer, Cell Culture, FGF Superfamily, Neurobiology, Proliferation, Stem cells & Differentiation, Wound Healing|
|Research Use Only. Not for use in diagnostic or therapeutic procedures.|